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Afreen Shariff


Dr. Shariff an Endocrinologist with a focus on endocrine disease in cancer patients specifically immune related endocrine toxicities.  She is board certified in Internal Medicine and in Endocrinology, Diabetes and Metabolism. She completed her graduate medical training at Deccan College of Medical Sciences followed by Internal Medicine residency at East Carolina University and fellowship in Endocrinology at Duke University School of Medicine. She has been a faculty at Duke since 2017. 

Over the last few years as a clinical endocrinologist and faculty at Duke, Dr. Shariff has developed collaborations with oncologists and established expertise in managing endocrine toxicities from immunotherapy. This is a new field in endocrinology with a small number of experts nationally. As part of her work, she works in tandem with oncologists and other sub-specialists to develop management protocols, streamline clinical care in complex oncology patients. She serves as the Associate Director for the Multi-Disciplinary Toxicity Program at the Center for Cancer Immunotherapy at Duke Cancer Institute. In addition, she is the founding Director for the Duke Endo-Oncology Program which is uniquely positioned to streamline care for cancer patients with new and pre-existing endocrine disease.  Apart from her clinical work, she strongly believes in the creative use of technology to enhance educational opportunities for learners. She produces and hosts a medical podcast series called CheckpointNOW that attracts audiences from around the world. 

Apart from work she enjoys exploring cultures through food and travel. She is an art and fitness enthusiast and enjoys time with her kids and husband.

Location :

Durham, North Carolina

Training :

East Carolina University/ Brody School of Medicine

Duke University School of Medicine

Board Certifications :

American Board of Internal Medicine

Endocrinology, Diabetes and Metabolism

Current Position :

Assistant Professor of Medicine, Duke University School of Medicine

Associate Director, Multi- Disciplinary Toxicity Program, Duke Cancer Institute

Affiliations :

Endocrine Society

American Association of Clinical Endocrinology